• In another study authors found that

  2024-11-18

  

  In another study, authors found that ADORA1 were present on the intrinsically photosensitive retinal ganglion hmg-coa reductase (ipRGCs), and application of adenosine to rat retinas reduced light-evoked spiking of ipRGCs through suppression of a cAMP-mediated pathway (Sodhi and Hartwick, 2014). The

• We further analyzed selected hit compounds for their

  2024-11-18

  

  We further analyzed selected hit compounds for their ability to inhibit human AdK in intact cells. Human 1321N1 astrocytoma glucose transporter were utilized which were found to express AdK. The whole cell assay was performed using a 96-well format. The standard AdK inhibitor 5-iodotubercidin was e

• PC is considered as a cancer of

  2024-11-18

  

  PC is considered as a cancer of the epigenome (Grasso et al., 2012, Robinson et al., 2015). Our results demonstrate that the interaction of AR with ACK1 drives the positive feedback epigenetic circuitry that is ultimately conducive to promote AR transcription. Further, this circuitry subjugates AR t

• The hypothalamic pituitary adrenal HPA axis is a neuroendocr

  2024-11-18

  

  The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that is central to regulating responses to stress (Palazidou, 2012). In older persons, a high dysfunction of the HPA axis is observed (Otte et al., 2005) which may be enhanced by stimulatory effects of genes involved in the axi

• The small fishers with little or no quota

  2024-11-18

  

  The small fishers with little or no quota who remained relied on quota leasing arrangements to continue their fishing operations. Such arrangements had relatively high transaction costs and by early 2000 it appeared that the demise of the small fisher was imminent [2]. The introduction in 2001 of t

• The overall adjustment the non toxicity and the addiction

  2024-11-18

  

  The overall adjustment, the non-toxicity and the addiction-free treatment methods are the advantages of EA. EA treatment for depression has achieved great clinical effect in recent years (Dong et al., 2017). The clinical practice guideline of the American college of physicians (ACP) have pointed out

• br Disclosure br Acknowledgement br Introduction CYP A is

  2024-11-18

  

  Disclosure Acknowledgement Introduction CYP17A1 is a multifunctional enzyme with both 17α-hydroxylase and 17,20-lyase activities and is essential for the biosynthesis of steroidal SANT-1 in male testes and adrenal glands. The 17α-hydroxylase activity of CYP17A1 is involved in the conversio

• In the present study we sought to

  2024-11-18

  

  In the present study we sought to decipher the role of ATP-citrate lyase and of the mitochondrial NADH-dependent Mae in the oleaginous yeast Y. lipolytica. Indeed, although this yeast is one of the major models for lipid metabolism, the function of these enzymes is still not clear. As the study of t

• Several genes related to metabolism post transcriptional

  2024-11-18

  

  Several genes related to metabolism, post-transcriptional regulation, chromatin structure, and signaling pathways are required for the sexual development and virulence of G. zeae (Baldwin et al., 2010, Bluhm et al., 2007, Ding et al., 2009, Han et al., 2007, Hou et al., 2002, Jenczmionka et al., 200

• br Materials and methods br

  2024-11-18

  

  Materials and methods Results Discussion In the present study, we found that SSTR2, SSTR5, and DA2R proteins are expressed in ACTH-positive XL413 hydrochloride synthesis in healthy canine pituitary glands, with particularly high positive cell ratios in the intermediate lobes. Somatostatin

• br Introduction Hepatocellular carcinoma HCC is an aggressiv

  2024-11-15

  

  Introduction Hepatocellular carcinoma (HCC) is an aggressive and malignant cancer detected in clinical practice, as it is the third key reason of tumor-related deaths worldwide, with > 800, 000 mortalities every year (Torre et al., 2015). Current treatments for HCC are surgical therapy, liver tra

• br APJ expression in metabolic diseases

  2024-11-15

  

  APJ expression in metabolic diseases Under physiological conditions, APJ is present in humans as well as in mouse tissues with high metabolic activity such as muscle and adipose tissue but not in the liver. Moreover, the presence and regulation of APJ in established adipocyte or muscle cell line

• AR 231453 In conclusion our data highlight

  2024-11-15

  

  In conclusion, our data highlight that variable anti-oxidative AR 231453 could be released through peptic hydrolysis of CMP fractions. Although casein hydrolysates produced a larger number of peptides (Table 1) with variable antioxidant capacities, all the peptides from whey hydrolysate exhibited h

• However from our meta analysis emerge

  2024-11-15

  

  However, from our meta-analysis emerge some strategic considerations for the continued use of antiangiogenic drugs for glioblastoma patients: Conflict of interest Funding Introduction Angiogenesis is a physiological process involving the formation of new blood vessels from pre-existing bl

• Recent genome wide association studies have indicated SORL a

  2024-11-15

  

  Recent genome-wide association studies have indicated SORL1 as a risk factor for AD (Meng et al., 2007, Rogaeva et al., 2007, Wen et al., 2013). SORL1, is expressed in neurons (Yin et al., 2015) and also regulates APP traffic from the cell membrane to the Golgi apparatus. A reduction in its expressi

13974 records 37/932 page Previous Next First page 上5页 3637383940 下5页 Last page